TUBERCULOSIS IN SIBERIAN AND FAR EASTERN FEDERAL DISTRICTS (2007-2016)


Deubiquitinases in hematological malignancies

Abstract Deubiquitinases (DUBs) are enzymes that control the stability, interactions or localization of most cellular proteins by here removing their ubiquitin modification.In recent years, some DUBs, such as USP7, USP9X and USP10, have been identified as promising therapeutic targets in hematological malignancies.Importantly, some potent inhibitor

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